2020年上海市科学技术奖提名公示(2)

发布者:科技处发布时间:2020-05-19浏览次数:170

我单位完成的下列项目拟申报推荐2020年度上海市科学技术奖,特进行公示。公示期:2020519日至2020526日,公示期内如对公示内容有异议,请您向科技处反映。联系人:张霞老师 联系电话:65882010

附:公示内容

1. 项目名称:肿瘤糖脂代谢显像的分子机制与应用转化

2. 知识产权情况:


国别

知识产权类别

授权号

名称

发明人

核心专利

中国

发明专利

CN101750502A

一种同步检测AFP和AFP-IgM的TRFIA及其试剂盒

盛世乐;黄钢;王青

中国

发明专利

CN100418966C

8-碘代咪唑并[1,2-a]吡啶-3-乙酰胺类化合物及制备方法

黄钢;李斌

中国

实用新型专利

CN203613193U

一种细胞代谢与呼吸的动态检测装置

黄钢;周翔;苗平

中国

实用新型专利

CN201501875U

恒流培养装置及使用其的γ射线动态监测装置

黄钢;盛世乐;宋少莉

中国

计算机软件著作权

2014SR081799

PET/CT诊断孤立性肺结节的智能软件V1.0

陈虞梅


3. 发表论文著作情况:


序号

论文著作

通讯作者

引用次数

1

Zhu Zongping, Zhao Xiaoping, Zhao Li, Yang Hao, Liu Liu, Li Jiajin, Wu Jianguo, Yang Fajun, Huang Gang, Liu Jianjun.p54(nrb)/NONO regulates lipid metabolism and breast cancer growth throughSREBP-1A [J]. Oncogene, 2016, 35(11): 1399-1410.

刘建军,黄钢

20

2

Huang Liangqian, Yu Zhenhai, Zhang Zhenchao, Ma Wenjing, Song Shaoli, Huang Gang. Interaction with PyruvateKinase M2 Destabilizes Tristetraprolin by Proteasome Degradation and RegulatesCell Proliferation in Breast Cancer [J]. Scientific Reports, 2016, 6: 22449.

黄钢

14

3

Liu Qiufang, Zhou Min, Li Panli, Ku Geng, Huang Gang, Li Chun, Song Shaoli. (64) CuS-labelednanoparticles: a new sentinel-lymph-node-mapping agent for PET-CT andphotoacoustic tomography [J]. Contrast Media & Molecular Imaging, 2016, 11(6): 475-481.

宋少莉

5

4

Xin Mei, Qiao Zhiguang, Li Jing, Liu Jianjun, Song Shaoli, Zhao Xiaoping, Miao Ping, Tang Tingtin, Wang Lei), Liu Weichun, Yang Xiaodi, Dai Kerong, Huang Gang. miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer andlung cancer [J]. Oncotarget, 2016, 7(28): 44252-44265.

黄钢,戴尅戎

64

5

Yang Hao, Zhao Xiaoping, Zhao Li, Liu Liu, Li Jiajin, Jia Wenzhi, Liu Jianjun, Huang Gang. PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma [J]. Oncotarget, 2016, 7(44): 72131-72147.

黄钢

10

6

Tang Shuang, Huang Gang, Fan Wei,  Chen Yue, Ward James M., Xu Xiaojiang, Xu Qing, Kang Ashley, McBurney Michael W., Fargo David C., Hu Guang, Baumgart-Vogt Eveline,  Zhao Yingming, Li Xiaoling. SIRT1-mediated deacetylation ofCRABPII regulates cellular retinoic acid signaling and modulates embryonic stemcell differentiation [J]. Molecular Cell, 2014, 55(6): 843-855.

黄钢,Li Xiaoling

32

7

Zhou Xiang, Chen Ruohua, Xie Wenhui, Ni Yicheng, Liu Jianjun, Huang Gang. Relationship between 18F-FDGaccumulation and lactate dehydrogenase A expression in lung adenocarcinomas [J]. Journal of Nuclear Medicine, 2014, 55(11): 1766-1771.

黄钢,刘建军

30

8

Huang Liangqian, Yu Zhenhai, Zhang Teng, Zhao Xiaoping, Huang Gang. HSP40 interacts with pyruvate kinase M2 and regulates glycolysis and cell proliferation in tumor cells [J]. PLoS One, 2014, 9(3): e92949.

黄钢

19

9

Yu Zhenhai, Ge Yingying, Xie Lei, Zhang Teng, Huang Liangqian, Zhao Xiaoping, Liu Jianjun, Huang Gang. Using a yeasttwo-hybrid system to identify FTCD as a new regulator for HIF-1α in HepG2 cells [J]. Cellular Signalling, 2014, 26(7): 1560-1566.

黄钢

10

10

Yu Zhenhai, Zhao Xiaoping, Huang Liangqian, Zhang Teng, Yang Fajun, Xie Lei, Song Shaoli, Miao Ping, Zhao Li, Sun Xiaoguang, Liu Jianjun, Huang Gang. Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells [J].Journal of Biological Chemistry, 2013, 288(49): 35406-35416.

黄钢,刘建军

44

11

Liu Yewei, Xie Reuben Qian, Wang Boshi, Shao Jiaxiang, Zhang Tingting, Liu Tengyuan, Huang GangXia Weiliang. Inhibition ofSIRT6 in prostate cancer reduces cell viability and increases sensitivity tochemotherapeutics [J]. Protein Cell, 2013, 4(9): 702-710.

夏伟梁,黄钢

45

12

Miao Ping, Sheng Shile, Sun Xiaoguang, Liu Jianjun, Huang Gang. Lactate dehydrogenase A in cancer: apromising target for diagnosis and therapy [J]. IUBMB Life, 2013, 65(11): 904-910.

黄钢

146

13

Zhang Chenpeng, Tong Jinlu, Huang Gang. Nicotinamide phosphoribosyl transferase (Nampt) is a target of microRNA-26b in colorectal cancer cells [J]. PLoS One, 2013, 8(7): e69963.

黄钢

34

14

Song Shaoli, Xiong Chiyi, Lu Wei, Ku Geng, Huang Gang, Li Chun. Apoptosis imaging probe predictsearly chemotherapy response in preclinical models: A comparative study with18F-FDG PET[J]. Journal of Nuclear Medicine, 2013, 54(1):104-110.

李春,黄钢

25

15

Ding Gang, Liu He-Dai, Huang Qian, Liang Hong-Xiang, Ding Zhao-Han, Liao Zhi-Jun, Huang Gang. HDAC6 promoteshepatocellular carcinoma progression by inhibiting P53 transcriptional activity [J]. FEBS Letters. 2013, 587(7): 880-886.

黄钢

40

16

Sheng Shi L., Liu Jian J., Dai Yun H., Sun Xiao G., Xiong Xiao P., Huang Gang. Knockdown of lactatedehydrogenase A suppresses tumor growth and metastasis of human hepatocellularcarcinoma [J]. FEBS Journal, 2012, 279(20): 3898-3910.

黄钢

118

17

Wang Yuting, Zhang Chengpeng, Liu Jianjun, Huang Gang. Is 18F-FDG PET accurate to predictneoadjuvant therapy response in breast cancer? A meta-analysis [J]. Breast Cancer Research and Treatment, 2012, 131(2): 357-369.

黄钢

75

18

Tang Shuang, Huang Gang, Liu Jianjun, Liu Tao, Treven Lyndal, Song Saoli, Zhang Chenpeng, Pan Lingling, Zhang Ting. Usefulness of 18F-FDG PET, combined FDG-PET/CT and EUS in diagnosing primarypancreatic carcinoma: a meta-analysis [J]. European Journal of Radiology,2011, 78(1): 142-150.

黄钢

59

19

Chen Yumei, Huang Gang, Sun Xiao Guang, Liu Jian Jun, Chen Tao, Shi Yi Ping, Wan Liang Rong. Optimizing delayed scan time for FDG PET: comparison of the early and late delayed scan [J]. Nuclear Medicine Communications, 2008, 29(5): 425‐430.

黄钢

26

20

Song Shao-Li, Liu Jian-Jun, Huang Gang, Wang Zhao-Hai, Song Yan-Yan, Sun Xiao-Guang, Chen Tao. Changes in 18F-FDGuptake within minutes after chemotherapy in a rabbit VX2 tumor model [J]. Journal of Nuclear Medicine,2008, 49(2): 303-309.

黄钢

33


4. 主要完成单位:上海健康医学院,上海交通大学医学院附属仁济医院,复旦大学附属肿瘤医院,上海市胸科医院

5. 主要完成人:黄钢,刘建军,宋少莉,谢文晖,杨浩,陈虞梅,周翔,陈若华

6. 提名者:上海市教育委员会

7. 提名等级:上海市科技进步奖二等奖